SRD5:Sewer Plague

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Sewer Plague is a disease in 5th edition Dungeons & Dragons.

Sewer plague is a generic term for a broad category of illnesses that incubate in sewers, refuse heaps, and stagnant swamps, and which are sometimes transmitted by creatures that dwell in those areas, such as rats and otyughs.

When a humanoid creature is bitten by a creature that carries the disease, or when it comes into contact with filth or offal contaminated by the disease, the creature must succeed on a DC 11 Constitution saving throw or become infected.

It takes 1d4 days for sewer plague’s symptoms to manifest in an infected creature. Symptoms include fatigue and cramps. The infected creature suffers one level of exhaustion, and it regains only half the normal number of hit points from spending Hit Dice and no hit points from finishing a long rest.

At the end of each long rest, an infected creature must make a DC 11 Constitution saving throw. On a failed save, the character gains one level of exhaustion. On a successful save, the character’s exhaustion level decreases by one level. If a successful saving throw reduces the infected creature’s level of exhaustion below 1, the creature recovers from the disease.

End of the SRD5 material

Disease Summary
Sewer Plague 
Targets: Humanoids

Primary Effects: fatigue, cramps, exhaustion

Incubation: 1-4 days

Vector: bite + exposure to infected filth or offal

Carriers: rats, vermin, otyughs

Deadly: True

Sources and Notes



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